章乐个人主页
个人简介
工作/教育背景
荣誉
社会服务
科研成果
在线服务
English
专利
章乐, 肖铭:多物种未出现k-mer子序列计算和特征分析方法及系统,ZL 2018 1 0207512.3 (中国国家知识产权局, 2018)
章乐, 高红杰:基于代理的多尺度药物协调预测方法,ZL 2017 1 156248.7 (中国国家知识产权局, 2017)
章乐, 李婷婷, 胡南& 何小玉: 一种高维少样本的基因,信号通路和相关蛋白质的选取方法. in Vol. ZL 2016 1 0734417. X (ed. 中国国家知识产权局) (中国, 2016)
章乐, 孔美静: 基于模块化因子图的骨髓瘤信号通路机制确认方法, 201610846098.1 (ed. 中国国家知识产权局) (中国, 2016)
章乐: 基于遗传和环境相关的结直肠癌数据模型的分析方法, 201610953314.2 (ed. 中国国家知识产权局) (中国, 2016)
章乐, 陈镜行, 丁维龙, 荆晨阳, 冯计平: 基于CPU-GPU异构复合式并行计算框架的密码子偏差系数模型方法,中国国家发明专利ZL 2017 1 0332575.7. 2017.
章乐, 尹凯凯, 李嘉坤:基于集成学习的脑出血预测模型建立方法及系统,中国国家知识产权局 ZL 201710691118.7.2017.
章乐、吴雯婷、刘宏图:高危型HPV型别和宫颈癌前病变阶段关系的计算方法及装置. 中国国家知识产权局 ZL 2019 11420979.7
章乐、张雷、吕骥:基于网络药理学的中药作用机制模型的建立方法、系统及装置. 中国国家知识产权局 ZL 2020 10260328.2
章乐,游宇杰,陈渝杰:高维度低样本基因数据筛选及蛋白质网络分析方法及系统. 中国国家知识产权局 ZL 2019 11424402.3
章乐,刘光迪,刘景祥,张伟,李雨辰,王越:心理健康综合自适应测评方法及系统. 中国国家知识产权局 ZL 2020 11351547.8
章乐,喻扬超,李冰:基于量子技术的基因搜索BLAST加速方法及系统. 中国国家知识产权局 ZL 2023 11254777.6
章乐 等:基于多组学数据的复发转移分析模型建立方法及系统. 中国国家知识产权局 ZL 2022 11198172.5
章乐 等: 一种基于量子计算的线性方程加速方法及系统. 中国国家知识产权局 ZL 2022 1 1427010.4
章乐 等: 一种量子计算纠错方法. 中国国家知识产权局 ZL 2022 1 1427009.1
著作
章乐:生物信息计算,科学出版社,ISBN 978-7-03-057077-2
章乐:系统生物学-重构网络的性质,重庆出版社,ISBN 978-7-229-12699-5
章乐:人工智能在肿瘤计算上的应用,科学出版社,ISBN 978-7-03-061799-6
章乐:Systems Medicine: Integrative Qualitative and Computational Approaches: A Brief Review of Current 3D Genomics Research,Elsevier, DOI:https://doi.org/10.1016/B978-0-12-801238-3.11594-6
章乐:Recent Research Advances in Biology Vol.10,B P International, DOI:https://doi.org/10.9734/bpi/rrab/v10/9995D
近年论文
Gao Jun,Lao Qicheng, Qingbo Kang, Liu Paul, Du Chenlin, Li Kang, Zhang Le*. (2024). Boosting Your Context by Dual Similarity Checkup for In-Context Learning Medical Image Segmentation. IEEE transactions on medical imaging. PP. 10.1109/TMI.2024.3440311.(IF: 8.9, 中科院一区)
Xiao M, Wei R, Yu J, Gao C, Yang F, Zhang L*. CpG island definition and methylation mapping of the T2T-YAO genome. Genomics, Proteomics & Bioinformatics. 2024. doi: 10.1093/gpbjnl/qzae009. (IF: 9.5, 中科院一区)
L. Zhang, W. Song, T. Zhu, Y. Liu, W. Chen, and Y. Cao, "ConvNeXt-MHC: improving MHC–peptide affinity prediction by structure-derived degenerate coding and the ConvNeXt model," Briefings in Bioinformatics, vol. 25, no. 3, p. , 2024. (IF: 9.5, 中科院一区)
Gao J, Lao Q, Liu P, Yi H, Kang Q, Jiang Z, Zhang L*et al. Anatomically Guided Cross-Domain Repair and Screening for Ultrasound Fetal Biometry. IEEE Journal of Biomedical and Health Informatics. 2023:1-12. doi: 10.1109/JBHI.2023.3298096. (IF: 7.7, 中科院一区)
You Y, Lai X, Pan Y, Zheng H, Vera J, Liu S, Zhang L*et al. Artificial intelligence in cancer target identification and drug discovery. Signal Transduct Target Ther. 2022;7(1):156. Epub 2022/05/11. doi: 10.1038/s41392-022-00994-0. PubMed PMID: 35538061; PubMed Central PMCID: PMCPMC9090746. (IF: 39.3, 中科院一区)
Song H, Chen L, Cui Y, Li Q, Wang Q, Fan J, Zhang L*et al. Denoising of MR and CT images using cascaded multi-supervision convolutional neural networks with progressive training. Neurocomputing. 2022;469:354-65. doi: 10.1016/j.neucom.2020.10.118. PubMed PMID: WOS:000761794800004. (IF: 6, 中科院一区)
Lai X, Zhou J, Wessely A, Heppt M, Maier A, Berking C, Zhang L* et al. A disease network-based deep learning approach for characterizing melanoma. Int J Cancer. 2022;150(6):1029-44. Epub 2021/10/31. doi: 10.1002/ijc.33860. PubMed PMID: 34716589. (IF: 6.4, 中科院一区)
Zhang L, Zhao J, Bi H, Yang X, Zhang Z, Su Y, et al. Bioinformatic analysis of chromatin organization and biased expression of duplicated genes between two poplars with a common whole-genome duplication. Hortic Res. 2021;8(1):62. Epub 2021/03/23. doi: 10.1038/s41438-021-00494-2. PubMed PMID: 33750794; PubMed Central PMCID: PMCPMC7943600. (IF: 8.7, 中科院一区)
Zhang L, Zhang L, Guo Y, Xiao M, Feng L, Yang C, et al. MCDB: A comprehensive curated mitotic catastrophe database for retrieval, protein sequence alignment, and target prediction. Acta Pharm Sin B. 2021;11(10):3092-104. Epub 2021/11/04. doi: 10.1016/j.apsb.2021.05.032. PubMed PMID: 34729303; PubMed Central PMCID: PMCPMC8546929. (IF: 14.5, 中科院一区)
Zhang L, Liu G, Kong M, Li T, Wu D, Zhou X, et al. Revealing dynamic regulations and the related key proteins of myeloma-initiating cells by integrating experimental data into a systems biological model. Bioinformatics. 2021;37(11):1554-61. Epub 2019/07/28. doi: 10.1093/bioinformatics/btz542. PubMed PMID: 31350562; PubMed Central PMCID: PMCPMC8485849. (IF: 5.8, 人工智能A)
Zhang L, Dai Z, Yu J, Xiao M. CpG-island-based annotation and analysis of human housekeeping genes. Brief Bioinform. 2021;22(1):515-25. Epub 2020/01/27. doi: 10.1093/bib/bbz134. PubMed PMID: 31982909. (IF: 9.5, 中科院一区)
Liu G-D, Li Y-C, Zhang W, Zhang L*. A Brief Review of Artificial Intelligence Applications and Algorithms for Psychiatric Disorders. Engineering-Prc. 2020;6(4):462-7. doi: 10.1016/j.eng.2019.06.008. PubMed PMID: WOS:000537705900015. (IF: 12.8, 中科院一区)
Zhang L, Bai W, Yuan N, Du Z. Comprehensively benchmarking applications for detecting copy number variation. PLoS Comput Biol. 2019;15(5):e1007069. Epub 2019/05/29. doi: 10.1371/journal.pcbi.1007069. PubMed PMID: 31136576; PubMed Central PMCID: PMCPMC6555534 Zdmedical, Information Polytron Technologies Inc. (IF: 4.779, 人工智能A)
Zhang L, Xiao M, Zhou J, Yu J. Lineage-associated underrepresented permutations (LAUPs) of mammalian genomic sequences based on a Jellyfish-based LAUPs analysis application (JBLA). Bioinformatics. 2018;34(21):3624-30. Epub 2018/05/16. doi: 10.1093/bioinformatics/bty392. PubMed PMID: 29762634. (IF: 5.8, 中科院一区)
Zhang L, Zhang S. Using game theory to investigate the epigenetic control mechanisms of embryo development: Comment on: "Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition" by Qian Wang et al. Phys Life Rev. 2017;20:140-2. Epub 2017/01/23. doi: 10.1016/j.plrev.2017.01.007. PubMed PMID: 28109753. (IF: 11.7, 中科院一区)
Zhang L, Liu Y, Wang M, Wu Z, Li N, Zhang J, et al. EZH2-, CHD4-, and IDH-linked epigenetic perturbation and its association with survival in glioma patients. Journal of molecular cell biology. 2017;9(6):477-88. Epub 2017/12/23. doi: 10.1093/jmcb/mjx056. PubMed PMID: 29272522; PubMed Central PMCID: PMCPMC5907834. (IF: 5.5, 中科院一区)
Zhang L, Qiao M, Gao H, Hu B, Tan H, Zhou X, et al. Investigation of mechanism of bone regeneration in a porous biodegradable calcium phosphate (CaP) scaffold by a combination of a multi-scale agent-based model and experimental optimization/validation. Nanoscale. 2016;8(31):14877-87. Epub 2016/07/28. doi: 10.1039/c6nr01637e. PubMed PMID: 27460959. (IF: 6.7, 中科院一区)